An In-Depth Topic Review of Systemic Lupus Erythematosus
May 20th, 2004For Physicians Michael D. Lockshin, MD 1. Definition 2. Pathogenesis 3. Clinical Presentation 4. Laboratory Findings 5. Differential Diagnosis 6. Initial Treatment 7. Long-term Management Issues 8. Prognosis 9. When to Refer 1. DefinitionLupus is both an acute and a chronic autoimmune, multisystem illness. Lupus has several forms: systemic (SLE), discoid (DLE, scarring rash only), drug-induced (DILE), and neonatal (NLE). For purposes of brevity, drug-induced lupus,[1] which is relatively rare, and discoid lupus are not discussed in this chapter. See the complete article on the Hospital for Special Surgery's web site